The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Nov. 30, 2011
Applicants:
David C. Tully, Emeryville, CA (US);
Paul Vincent Rucker, Carlsbad, CA (US);
Phillip B. Alper, San Diego, CA (US);
Daniel Mutnick, San Diego, CA (US);
Donatella Chianelli, San Diego, CA (US);
Inventors:
David C. Tully, Emeryville, CA (US);
Paul Vincent Rucker, Carlsbad, CA (US);
Phillip B. Alper, San Diego, CA (US);
Daniel Mutnick, San Diego, CA (US);
Donatella Chianelli, San Diego, CA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 451/06 (2006.01); C07D 519/00 (2006.01); C07H 17/00 (2006.01); A61K 45/06 (2006.01); A61K 31/46 (2006.01); A61K 31/506 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/4709 (2006.01); A61K 31/5025 (2006.01); A61K 31/706 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 451/06 (2013.01); A61K 31/46 (2013.01); A61K 31/4709 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 31/706 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01); C07H 17/00 (2013.01);
Abstract
The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X receptors (FXR).