The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Dec. 29, 2008
Applicants:

Wilfried Hornberger, Ludwigshafen, DE;

Helmut Mack, Ludwigshafen, DE;

Andreas Kling, Ludwigshafen, DE;

Achim Moeller, Ludwigshafen, DE;

Barbara Vogg, Ludwigshafen, DE;

Jürgen Delzer, Ludwigshafen, DE;

Gisela Backfisch, Ludwigshafen, DE;

Armin Beyerbach, Ludwigshafen, DE;

Inventors:

Wilfried Hornberger, Ludwigshafen, DE;

Helmut Mack, Ludwigshafen, DE;

Andreas Kling, Ludwigshafen, DE;

Achim Moeller, Ludwigshafen, DE;

Barbara Vogg, Ludwigshafen, DE;

Jürgen Delzer, Ludwigshafen, DE;

Gisela Backfisch, Ludwigshafen, DE;

Armin Beyerbach, Ludwigshafen, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); A61K 31/4439 (2006.01); C07D 491/052 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07D 491/052 (2013.01);
Abstract

The present invention relates to novel carboxamide compounds of the formula I and their use for the manufacture of a medicament. The carboxamide compounds are prodrugs of inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity.


Find Patent Forward Citations

Loading…