The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Apr. 03, 2014
Applicant:
Janssen Pharmaceutica N. V., Beerse, BE;
Inventors:
Marc Gustaaf Celine Verdonck, Gierle, BE;
Patrick Rene Angibaud, Fontaine-Bellenger, FR;
Bruno Roux, Saint Leger du Bourg-Denis, FR;
Isabelle Noelle Constance Pilatte, Louviers, FR;
Peter Ten Holte, Beerse, BE;
Janine Arts, Breda, NL;
Kristof Van Emelen, Sint-Niklaas, BE;
Assignee:
Janssen Pharmaceutica N. V., Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/4545 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 491/04 (2006.01); C07D 491/056 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 491/04 (2013.01); C07D 491/056 (2013.01);
Abstract
This invention comprises the novel compounds of formula (I) wherein R, R, R, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.