The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Jun. 14, 2011
Applicants:
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Dilip Ramdas Birari, Maharashtra, IN;
Inventors:
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Dilip Ramdas Birari, Maharashtra, IN;
Assignee:
Cipla Limited, Mumbai, IN;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 229/00 (2006.01); C07C 231/12 (2006.01);
U.S. Cl.
CPC ...
C07C 231/12 (2013.01); C07C 2101/14 (2013.01);
Abstract
The present invention relates to a process for the preparation of substantially pure nateglinide of formula (I), substantially free from the cis-isomer and L-enantiomer and preparation of enantiomerically pure nateglinide form B, directly from the hydrolysis of a (−)-N-(trans-4-isopropylcyclohexyl-1-carbonyl)-D-phenylalanine alkyl ester in a ketonic solvent or water or mixture thereof.