The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Nov. 24, 2008
Peter John Bonitatibus, Jr., Saratoga Springs, NY (US);
David Cheney Demoulpied, New Baltimore, NY (US);
Andrew Soliz Torres, Troy, NY (US);
Amit Mohan Kulkarni, Clifton Park, NY (US);
Robert Edgar Colborn, Niskayuna, NY (US);
Paul William Buckley, Scotia, NY (US);
Peter John Bonitatibus, Jr., Saratoga Springs, NY (US);
David Cheney deMoulpied, New Baltimore, NY (US);
Andrew Soliz Torres, Troy, NY (US);
Amit Mohan Kulkarni, Clifton Park, NY (US);
Robert Edgar Colborn, Niskayuna, NY (US);
Paul William Buckley, Scotia, NY (US);
General Electric Company, Niskayuna, NY (US);
Abstract
The present invention is generally directed to core/shell nanoparticles, wherein such core/shell nanoparticles comprise a nanoparticle core and a nanoshell disposed about the nanoparticle core such that, in the aggregate, they form a core/shell nanoparticle that is operable for use as an imaging agent in X-ray/computed tomography (CT). Typically, such core/shell nanoparticle-based X-ray CT imaging agents further comprise a targeting species for targeting the imaging agent to diseased sites. Included herein are methods for forming such agents, comprising forming an ensemble of core/shell nanoparticles, wherein the mean diameter of the ensemble of core/shell nanoparticles is selected so as to render the nanoparticles in the ensemble substantially clearable by a mammalian kidney.