The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Apr. 28, 2009
Applicants:
Takeshi Nakanishi, Tokyo, JP;
Kazuhisa Hara, Tokyo, JP;
Chieko Seno, Tokyo, JP;
Inventors:
Assignee:
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 47/34 (2006.01); A61K 31/785 (2006.01); C08G 69/10 (2006.01); C08G 69/40 (2006.01); C08G 69/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48315 (2013.01); A61K 31/785 (2013.01); A61K 47/34 (2013.01); A61K 47/48215 (2013.01); C08G 69/10 (2013.01); C08G 69/40 (2013.01); C08G 69/48 (2013.01);
Abstract
Disclosed is a polymer conjugate of folic acid or a folic acid derivative, wherein an amide bond is not used. The compound has chemical stability and adequate drug release rate in the living organism. Specifically disclosed is a polymer conjugate of folic acid or a folic acid derivative, wherein a substituent represented by formula (I) is bonded to a carboxy group of a block copolymer which is composed of a polyethylene glycol and a polymer having a carboxy group in a side chain, or a pharmacologically acceptable salt thereof.