The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Mar. 11, 2013
Orthovita, Inc., Malvern, PA (US);
Venkat R. Garigapati, Southborough, MA (US);
Orthovita, Inc., Malvern, PA (US);
Abstract
Compositions comprising thrombin and collagen and methods of preparation thereof are disclosed herein. In one embodiment, a composition comprises thrombin and collagen in an aqueous buffer solution, wherein the buffer solution includes at least one of a first compound represented by Formula I: R—C(O)—OM, wherein Ris —CH, —CHCHC(O)OH, or —CHCHC(O)OM, and wherein Mis a monovalent ion; or a second compound represented by Formula II: R—C(O)—OMO—C(O)—R, wherein Ris —CHor —CHCH, and wherein Mis a divalent ion. In one embodiment, the buffer solution includes sodium acetate, calcium propionate, and sorbitol.