The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Aug. 18, 2011
Yoon Jin Lee, Seoul, KR;
Yun-sil Lee, Seoul, KR;
Hae-june Lee, Hwaseong-si, KR;
Seo-hyun Choi, Seoul, KR;
Kyeng-jung Kim, Seoul, KR;
Yoon Jin Lee, Seoul, KR;
Yun-Sil Lee, Seoul, KR;
Hae-June Lee, Hwaseong-si, KR;
Seo-Hyun Choi, Seoul, KR;
Kyeng-Jung Kim, Seoul, KR;
Abstract
The present invention provides a pharmaceutical composition for suppressing angiogenesis, containing heat shock protein 27 (HSP27) or a nucleic acid encoding HSP27. In addition, the present invention provides a pharmaceutical composition for treating cancer, containing HSP27 or a nucleic acid encoding HSP27. Additionally, the present invention provides a method of suppressing the in vitro growth of endothelial cells using HSP27. Further, the present invention provides a method of screening an active material for suppressing angiogenesis or an active material for treating cancer, comprising the following steps: processing endothelial cell lines into samples, respectively; measuring the content of HSP27 in an endothelial cell line; and selecting the sample in which the content of HSP27 in an endothelial cell line is increased compared with a control group.