The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Nov. 30, 2004
Applicants:

Rudolph Ernest Lisa, Grosse Ile, MI (US);

Anisul Quadir, Hackettstown, NJ (US);

Rebecca Ham Scheper, Mount Arlington, NJ (US);

Peter Grzesowski, Boonton, NJ (US);

Inventors:

Rudolph Ernest Lisa, Grosse Ile, MI (US);

Anisul Quadir, Hackettstown, NJ (US);

Rebecca Ham Scheper, Mount Arlington, NJ (US);

Peter Grzesowski, Boonton, NJ (US);

Assignee:

BASF CORPORATION, Florham Park, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 47/34 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/146 (2013.01); A61K 9/2031 (2013.01); A61K 47/34 (2013.01);
Abstract

A method for formation of micro-prilled poloxamer particles is disclosed. The particles find special use in pharmaceutical formulations. The process involves use of atomizing nozzles at higher than normal pressure atomizing gas, high atomizing gas temperature, use of high feed temperatures to reduce the viscosity of the poloxamer and optionally sieving after prill formation in prilling towers. The poloxamer particles are spherical and preferably have an average nominal diameter of less than or equal to 106 microns. The process is very cost effective and rapid.


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