The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Oct. 13, 2011
Applicants:

Andrea Pfeifer, St. Legier, CH;

Maria Pihlgren, Mont-sur-Lausanne, CH;

Andreas Muhs, Cugy, CH;

Inventors:

Andrea Pfeifer, St. Legier, CH;

Maria Pihlgren, Mont-sur-Lausanne, CH;

Andreas Muhs, Cugy, CH;

Assignee:

AC IMMUNE S.A., Lausanne, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C07K 16/18 (2013.01); A61K 39/0007 (2013.01); A61K 39/3955 (2013.01); A61K 47/48815 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01);
Abstract

The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of β-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD).


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