The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Feb. 09, 2012
Applicants:

Shuji Higashi, Tokyo, JP;

Yutaka Nagai, Tokyo, JP;

Shotaro Fujii, Tokyo, JP;

Inventors:

Shuji Higashi, Tokyo, JP;

Yutaka Nagai, Tokyo, JP;

Shotaro Fujii, Tokyo, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/49 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); G01N 33/5002 (2013.01); G01N 33/491 (2013.01); G01N 33/492 (2013.01); G01N 33/5306 (2013.01); G01N 2800/32 (2013.01);
Abstract

An object of the present invention is to provide a method which is capable of carrying out detection and evaluation of the vascular endothelial damage with a high degree of accuracy. According to an aspect of the present invention, there is provided a method for testing vascular endothelial damage with respect to a blood sample collected from living organism comprising the steps of: 1) detecting or determining quantitatively vascular endothelial cell-derived microparticle; and 2) detecting or determining quantitatively tissue factor-containing microparticle. Furthermore, according to another aspect of the present invention, there is provided a testing kit of vascular endothelial damage comprising a first antibody which specifically recognizes the vascular endothelium-derived microparticle, and a second antibody which specifically recognizes the tissue factor-containing microparticle.


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