The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Apr. 11, 2008
Applicants:

Ken Nishimura, Tsukuba, JP;

Hiroaki Segawa, Tsukuba, JP;

Mahito Nakanishi, Tsukuba, JP;

Inventors:

Ken Nishimura, Tsukuba, JP;

Hiroaki Segawa, Tsukuba, JP;

Mahito Nakanishi, Tsukuba, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C07H 21/02 (2006.01); C12N 7/01 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01); A01N 63/00 (2006.01); C12N 15/86 (2006.01); A61K 38/16 (2006.01); C12N 7/00 (2006.01); A61K 35/12 (2015.01); A61K 35/13 (2015.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 38/162 (2013.01); C12N 7/00 (2013.01); A61K 35/12 (2013.01); A61K 35/13 (2013.01); C12N 2760/18821 (2013.01); C12N 2760/18843 (2013.01);
Abstract

A persistently infective virus vector is produced by using a gene so modified as to encode an amino acid sequence including a valine substituted for an amino acid residue at position-1618 in the amino acid sequence for an L protein of a persistently non-infective Sendai virus. A non-transmissible, persistently infective virus vector is also produced by defecting or deleting at least one of M gene, F gene, and HN gene. These virus vectors have no cytotoxicity, can achieve the sustained gene expression over a long period of time, is safe, and is therefore useful.


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Nishimura, Ken. (2015). [object object] (U.S. Patent No. 9145564). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9145564

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