The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Sep. 08, 2011
Applicants:

Veronica Fowler, Alton, GB;

Nick Knowles, Aldershot, GB;

Paul Barnett, Windlesham, GB;

Inventors:

Veronica Fowler, Alton, GB;

Nick Knowles, Aldershot, GB;

Paul Barnett, Windlesham, GB;

Assignee:

THE PIRBRIGHT INSTITUTE, Pirbright, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/135 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/135 (2013.01); C07K 14/005 (2013.01); C12N 2770/32122 (2013.01); C12N 2770/32134 (2013.01);
Abstract

The present invention provides a foot and mouth disease (FMD) virus having improved stability compared to the field isolate of the same subtype, wherein the virus comprises one or more amino acid mutations along a line of symmetry of the capsid structure. The present invention also relates to a vaccine comprising such an FMD virus and its use to prevent foot and mouth disease.


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