The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2015
Filed:
Dec. 03, 2010
Jiwu Wang, La Jolla, CA (US);
Robert Earl Campbell, Edmonton, CA;
Hiofan Hoi, Edmonton, CA;
Nathan Christopher Shaner, Seaside, CA (US);
Jiwu Wang, La Jolla, CA (US);
Robert Earl Campbell, Edmonton, CA;
Hiofan Hoi, Edmonton, CA;
Nathan Christopher Shaner, Seaside, CA (US);
Allele Biotechnology & Pharmaceuticals, Inc., San Diego, CA (US);
University of Alberta, TEC Edmonton, Edmonton, CA;
Abstract
The present disclosure provides an isolated nucleic acid sequence encoding a monomeric photoconvertible fluorescent protein, and fragments and derivatives thereof. Also provided is a method for engineering the nucleic acid sequence, a vector comprising the nucleic acid sequence, a host cell comprising the vector, and use of the vector in a method for expressing the nucleic acid sequence. The present disclosure further provides an isolated nucleic acid, or mimetic or complement thereof, that hybridizes under stringent conditions to the nucleic acid sequence. Additionally, the present provides a monomeric photoconvertible fluorescent protein encoded by the nucleic acid sequence, as well as derivatives, fragments, and homologues thereof. Also provided is an antibody that specifically binds to the photoconvertible fluorescent protein.