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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9145415 B1

PDFFull Text
Date of Patent:
Sep. 29, 2015

Filed:

Oct. 16, 2014

Nitrogen-containing heterocyclic compound or salt thereof

Applicant:

Fujifilm Corporation, Tokyo, JP;

Inventors:

Masaru Takasaki, Ashigarakami-gun, JP;

Toshiaki Tsujino, Ashigarakami-gun, JP;

Shintarou Tanabe, Ashigarakami-gun, JP;

Megumi Ookubo, Ashigarakami-gun, JP;

Kimihiko Sato, Ashigarakami-gun, JP;

Atsush Hirai, Ashigarakami-gun, JP;

Daisuke Terada, Ashigarakami-gun, JP;

Shinsuke Inuki, Ashigarakami-gun, JP;

Shinsuke Mizumoto, Ashigarakami-gun, JP;

Assignee:

FUJIFILM Corporation, Tokyo, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Alexander R Pagano

Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 471/04 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 213/74 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 239/48 (2006.01); C07D 239/49 (2006.01); C07D 409/12 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 213/74 (2013.01); C07D 239/48 (2013.01); C07D 239/49 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); A61K 31/44 (2013.01); A61K 31/505 (2013.01);
Abstract

The object is to provide an Fms-like tyrosine kinase 3 (FLT3) inhibitor useful as a therapeutic agent for acute myeloid leukemia (AML). A novel nitrogen-containing heterocyclic compound represented by the general formula [1] or a salt thereof is provided. The compound or a salt thereof of the present invention can be used as an active ingredient of a pharmaceutical composition for a treatment of a disease or condition relating to FLT3, such as acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).

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