The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Sep. 28, 2012
Applicant:

Taiho Pharmaceutical Co., Ltd., Chiyoda-ku, JP;

Inventors:

Toshihiro Sakamoto, Moriya, JP;

Takashi Mita, Tsukuba, JP;

Kazuaki Shibata, Tsukuba, JP;

Yoshio Ogino, Tsukuba, JP;

Hideya Komatani, Toride, JP;

Assignee:
Attorney:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); A61K 31/53 (2006.01); A61K 31/535 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/53 (2013.01); A61K 31/535 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention provides a compound represented by the following general formula (I) or a salt thereof which has a Syk inhibitory effect (in the formula Rrepresents a hydrogen atom or an optionally substituted C-Calkyl group; A represents a hydrogen atom, an optionally substituted C-Calkyl group, an optionally substituted C-Calkenyl group, an optionally substituted C-Calkynyl group, an optionally substituted C-Ccycloalkyl group, an optionally substituted C-Caromatic hydrocarbon group, an optionally substituted 4- to 10-membered unsaturated heterocyclic group, or an optionally substituted 4- to 10-membered saturated heterocyclic group, or optionally forms a 4- to 10-membered unsaturated heterocyclic ring or a 4- to 10-membered saturated heterocyclic ring together with Rand the nitrogen atom bonded thereto; Rrepresents a hydrogen atom or an optionally substituted C-Calkyl group; and B represents an optionally substituted unsaturated heterocyclic group).


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