The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2015
Filed:
May. 04, 2012
Denis Deschenes, Lachine, CA;
Michael D. Altman, Needham, MA (US);
John Michael Ellis, Needham, MA (US);
Christian Fischer, Natick, MA (US);
Andrew M. Haidle, Cambridge, MA (US);
Solomon D. Kattar, Arlington, MA (US);
Alan B. Northrup, Reading, MA (US);
Adam J. Schell, Decatur, GA (US);
Graham F. Smith, Sudbury, MA (US);
Brandon M. Taoka, Hoboken, NJ (US);
Corey Bienstock, Natick, MA (US);
Maria Emilia Di Francesco, Houston, TX (US);
Anthony Donofrio, Cambridge, MA (US);
Scott Peterson, Salem, MA (US);
Kerrie B. Spencer, Woonsocket, RI (US);
James Patrick Jewell, Somerville, MA (US);
Amjad Ali, Freehold, NJ (US);
David Jonathan Bennett, Doylestown, PA (US);
Qun Dang, Westfield, NJ (US);
John Wai, Harleysville, PA (US);
Denis Deschenes, Lachine, CA;
Michael D. Altman, Needham, MA (US);
John Michael Ellis, Needham, MA (US);
Christian Fischer, Natick, MA (US);
Andrew M. Haidle, Cambridge, MA (US);
Solomon D. Kattar, Arlington, MA (US);
Alan B. Northrup, Reading, MA (US);
Adam J. Schell, Decatur, GA (US);
Graham F. Smith, Sudbury, MA (US);
Brandon M. Taoka, Hoboken, NJ (US);
Corey Bienstock, Natick, MA (US);
Maria Emilia Di Francesco, Houston, TX (US);
Anthony Donofrio, Cambridge, MA (US);
Scott Peterson, Salem, MA (US);
Kerrie B. Spencer, Woonsocket, RI (US);
James Patrick Jewell, Somerville, MA (US);
Amjad Ali, Freehold, NJ (US);
David Jonathan Bennett, Doylestown, PA (US);
Qun Dang, Westfield, NJ (US);
John Wai, Harleysville, PA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Canada Inc., Quebec, CA;
Abstract
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.