The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2015

Filed:

Dec. 18, 2008
Applicants:

Johan Bylund, Södertälje, SE;

Maria E Ek, Södertälje, SE;

Ylva Gravenfors, Södertälje, SE;

Gunnar Nordvall, Södertälje, SE;

Alexander Minidis, Södertälje, SE;

Karl S. a Vallin, Södertälje, SE;

Jenny Viklund, Södertälje, SE;

Jörg Holenz, Södertälje, SE;

Stefan Von Berg, Södertälje, SE;

Daniel Sohn, Södertälje, SE;

Inventors:

Johan Bylund, Södertälje, SE;

Maria E Ek, Södertälje, SE;

Ylva Gravenfors, Södertälje, SE;

Gunnar Nordvall, Södertälje, SE;

Alexander Minidis, Södertälje, SE;

Karl S. A Vallin, Södertälje, SE;

Jenny Viklund, Södertälje, SE;

Jörg Holenz, Södertälje, SE;

Stefan Von Berg, Södertälje, SE;

Daniel Sohn, Södertälje, SE;

Assignee:

Astrazeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 303/00 (2006.01); C07C 307/00 (2006.01); C07C 309/00 (2006.01); C07C 311/00 (2006.01); A01N 41/06 (2006.01); A61K 31/16 (2006.01); C07D 307/79 (2006.01); C07C 311/39 (2006.01); C07C 323/67 (2006.01); C07D 209/08 (2006.01); C07D 209/10 (2006.01); C07D 213/30 (2006.01); C07D 213/61 (2006.01); C07D 213/64 (2006.01); C07D 239/34 (2006.01); C07D 265/36 (2006.01); C07D 271/10 (2006.01); C07D 277/32 (2006.01); C07D 307/38 (2006.01); C07D 307/91 (2006.01); C07D 333/34 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
C07D 307/79 (2013.01); C07C 311/39 (2013.01); C07C 323/67 (2013.01); C07D 209/08 (2013.01); C07D 209/10 (2013.01); C07D 213/30 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 239/34 (2013.01); C07D 265/36 (2013.01); C07D 271/10 (2013.01); C07D 277/32 (2013.01); C07D 307/38 (2013.01); C07D 307/91 (2013.01); C07D 333/34 (2013.01); C07D 409/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/10 (2013.01); C07C 2102/08 (2013.01); C07C 2102/10 (2013.01);
Abstract

The invention provides compounds of formula (I) wherein R, R, L, L, G, G, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.


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