logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9145354 B1

PDFFull Text
Date of Patent:
Sep. 29, 2015

Filed:

Oct. 31, 2012

Pharmaceutical compounds

Applicant:

Astex Therapeutics Limited, Cambridge, GB;

Inventors:

Andrew James Woodhead, Cambridge, GB;

Christopher Charles Frederick Hamlett, Cambridge, GB;

Gilbert Ebai Besong, Bad Duerkheim, DE;

Gianni Chessari, Cambridge, GB;

Maria Grazia Carr, Cambridge, GB;

Alessia Millemaggi, Cambridge, GB;

David Norton, Cambridge, GB;

Susanne Maria Saalau-Bethell, Cambridge, GB;

Hendrika Maria Gerarda Willems, Cambridge, GB;

Neil Thomas Thompson, Cambridge, GB;

Steven Douglas Hiscock, Royston, GB;

Assignee:

ASTEX THERAPEUTICS LIMITED, Cambridge, GB;

Attorney:

Heslin Rothenberg Farley & Mesiti P.C.

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
C07C 225/16 (2006.01); C07D 213/73 (2006.01); C07D 213/74 (2006.01); C07C 255/58 (2006.01); C07D 213/79 (2006.01); C07D 213/81 (2006.01); C07D 213/84 (2006.01); C07D 213/89 (2006.01); C07D 231/12 (2006.01); C07D 401/04 (2006.01); C07D 239/26 (2006.01); C07D 239/38 (2006.01); C07C 225/18 (2006.01); C07D 241/20 (2006.01); C07D 261/08 (2006.01); C07D 277/28 (2006.01); C07D 498/04 (2006.01); C07D 213/50 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07C 225/22 (2006.01); C07C 229/38 (2006.01); C07C 237/06 (2006.01); C07C 237/10 (2006.01); C07C 237/24 (2006.01); C07C 237/30 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); C07C 313/06 (2006.01); A61K 31/138 (2006.01); A61K 31/277 (2006.01); A61K 31/42 (2006.01); A61K 31/425 (2006.01); A61K 31/44 (2006.01); A61K 31/4965 (2006.01); A61K 31/505 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01); C07C 221/00 (2006.01); C07C 253/30 (2006.01); C07D 275/02 (2006.01); A61K 47/10 (2006.01); A61K 47/26 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
C07C 225/16 (2013.01); A61K 9/0019 (2013.01); A61K 9/2018 (2013.01); A61K 9/4858 (2013.01); A61K 31/138 (2013.01); A61K 31/277 (2013.01); A61K 31/42 (2013.01); A61K 31/425 (2013.01); A61K 31/44 (2013.01); A61K 31/4965 (2013.01); A61K 31/505 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); C07C 221/00 (2013.01); C07C 225/18 (2013.01); C07C 225/22 (2013.01); C07C 229/38 (2013.01); C07C 237/06 (2013.01); C07C 237/10 (2013.01); C07C 237/24 (2013.01); C07C 237/30 (2013.01); C07C 253/30 (2013.01); C07C 255/58 (2013.01); C07C 313/06 (2013.01); C07D 213/50 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 213/73 (2013.01); C07D 213/74 (2013.01); C07D 213/79 (2013.01); C07D 213/81 (2013.01); C07D 213/84 (2013.01); C07D 213/89 (2013.01); C07D 231/12 (2013.01); C07D 239/26 (2013.01); C07D 239/38 (2013.01); C07D 241/20 (2013.01); C07D 261/08 (2013.01); C07D 275/02 (2013.01); C07D 277/28 (2013.01); C07D 401/04 (2013.01); C07D 498/04 (2013.01); A61K 9/19 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); C07B 2200/05 (2013.01); C07C 2101/02 (2013.01);
Abstract

The invention provides compounds that are useful in the treatment of hepatitis C virus (HCV) infections. The compounds have the formula (1): or a salt, N-oxide, tautomer or stereoisomer thereof, wherein A is CH or N; E is CH or N;

Find Patent Forward Citations

Loading…