The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9144613 B1

Date of Patent:

Sep. 29, 2015

Filed:

Jan. 16, 2014

Halogenated phenols for diagnostics, antioxidant protection and drug delivery

Applicant:

Keith R. Latham, Johnson City, TN (US);

Inventor:

Keith R. Latham, Johnson City, TN (US);

Assignee:

Other;

Attorney:

Stockwell & Smedley, PSC

Primary Examiner:

Johann R Richter

Assistant Examiner:

Katherine Peebles

Int. Cl.

CPC ...

A61K 49/00 (2006.01); G01N 33/52 (2006.01); A61K 51/04 (2006.01); A61K 49/04 (2006.01); A61K 47/48 (2006.01); C07C 43/295 (2006.01); C07C 217/60 (2006.01); C07C 323/52 (2006.01); C07C 229/36 (2006.01); C07C 233/25 (2006.01); C07D 475/08 (2006.01); C07D 489/02 (2006.01); C07D 499/887 (2006.01); C07D 209/36 (2006.01); C07J 1/00 (2006.01); C07J 5/00 (2006.01);

U.S. Cl.

CPC ...

A61K 47/48023 (2013.01); A61K 49/006 (2013.01); A61K 49/0438 (2013.01); A61K 51/0446 (2013.01); C07C 43/295 (2013.01); C07C 217/60 (2013.01); C07C 229/36 (2013.01); C07C 233/25 (2013.01); C07C 323/52 (2013.01); C07D 209/36 (2013.01); C07D 475/08 (2013.01); C07D 489/02 (2013.01); C07D 499/897 (2013.01); C07J 1/0022 (2013.01); C07J 5/0053 (2013.01); G01N 33/52 (2013.01); Y10T 436/145555 (2015.01);

Abstract

The present invention relates to a composition and method for the detection of a detectable product formed from a compound of the present invention in the body of an individual. The detectable product may include a halide or a benzenetriol-based or benzenetetrol-based product of a dehalogenation reaction in the presence of FROS. In many embodiments, an indigo-like product formed from an indigogenic compound of the present invention may also be a detectable product for diagnostic purposes. This indigo-like product may have a higher residence time in tissues where it is formed, thus providing a detectable product localized to sites of high FROS. An indigogenic compound containing one or more radioactive isotopes is further provided for therapeutic purposes.

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