The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2015
Filed:
May. 05, 2014
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
National Research Council of Canada, Ottawa, CA;
John B. Robbins, New York, NY (US);
Rachel Schneerson, Bethesda, MD (US);
Joanna Kubler-Kielb, Bethesda, MD (US);
Christopher P. Mocca, Columbia, MD (US);
Evguenii Vinogradov, Ottawa, CA;
The United States of America, as represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
National Research Council of Canada, Ottawa, CA;
Abstract
Disclosed are immunogenic conjugates and therapeutic compositions that include such immunogenic conjugates. Also disclosed are methods of treating and/or inhibiting aninfection. The disclosed immunogenic conjugates have the general structure:Pr—Sr—O—N═C-Kdo-OSwherein Pr is a carrier protein, Sr is an optional spacer moiety, Kdo is an 3-deoxy-D-manno-octulosonic acid or a derivative thereof, and OS is an oligosaccharide or polysaccharide obtained from. In specific examples, the immunogenic conjugates include the core oligosaccharide obtained fromhaving the structure: In specific examples, the disaccharide repeat unit included in the immunogenic conjugate has the structure:α-L-AltNAcA-3-β-FucNAc4N-4-.