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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9139829 B1

PDFFull Text
Expired
Date of Patent:
Sep. 22, 2015

Filed:

Feb. 26, 2013

Sirna targeting ets1 and elk1 and method of using same in the inhibition of cip2a gene in cancer treatment

Applicant:

Medical Diagnostic Laboratories, Llc, Hamilton, NJ (US);

Inventors:

Lyndi M. Rice, Philadelphia, PA (US);

Rajash Pallai, West Chester, PA (US);

Assignee:

Medical Diagnostic Laboratories, LLC, Hamilton, NJ (US);

Attorney:

Siu K. Lo

Primary Examiner:

Brian Whiteman

Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); C07K 14/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); C07K 14/82 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract

Disclosed are methods of attenuating activity of the gene promoter of CIP2A. siRNAs are used to target against Ets1 and Elk1 transcriptional factors, thereby blocking the binding of Ets1 and Elk1 to the CIP2A gene promoter. It is disclosed that the siRNAs targeted against Ets1 and Elk1 attenuate the gene expression of CIP2A. A kit containing siRNA reagents for attenuating the CIP2A gene expression is also disclosed.

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Rice, Lyndi. (2015). Sirna targeting ets1 and elk1 and method of using same in the inhibition of cip2a gene in cancer treatment (U.S. Patent No. 9139829). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9139829

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