The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2015
Filed:
Nov. 11, 2010
Applicants:
Gerard Johannes Platenburg, Voorschoten, NL;
Josephus Johannes DE Kimpe, Utrecht, NL;
Judith Christina Theodora Van Deutekom, Dordrecht, NL;
Garrit-jan Boudewijn Van Ommen, Amsterdam, NL;
Annemieke Aartsma-rus, BE Hoofddorp, NL;
Inventors:
Gerard Johannes Platenburg, Voorschoten, NL;
Josephus Johannes de Kimpe, Utrecht, NL;
Judith Christina Theodora van Deutekom, Dordrecht, NL;
Garrit-Jan Boudewijn van Ommen, Amsterdam, NL;
Annemieke Aartsma-Rus, BE Hoofddorp, NL;
Assignees:
Prosensa Technologies B.V., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/346 (2013.01); C12N 2310/3517 (2013.01); C12N 2320/33 (2013.01);
Abstract
The invention relates to oligonucleotides that bind to and induce skipping of exon 44 in the human dystrophin pre-mRNA, and methods of use.