The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2015
Filed:
Sep. 02, 2011
Applicants:
Einar Sigurdsson, New York, NY (US);
Ayodeji Asuni, New York, NY (US);
Inventors:
Einar Sigurdsson, New York, NY (US);
Ayodeji Asuni, New York, NY (US);
Assignee:
New York University, New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A01N 37/18 (2006.01); C07K 16/18 (2006.01); A61K 9/00 (2006.01); C07K 14/47 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 9/0019 (2013.01); C07K 14/4711 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01);
Abstract
The present invention relates to methods of treating and preventing Alzheimer's Disease or other tauopathies in a subject by administering a tau protein, its immunogenic epitopes, or antibodies recognizing the tau protein or its immunogenic epitopes under conditions effective to treat or prevent Alzheimer's Disease of other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tangle-related behavioral phenotype in a subject.