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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9139604 B1

PDFFull Text
Date of Patent:
Sep. 22, 2015

Filed:

Jun. 19, 2014

Antiviral phosphonate analogs

Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Constantine G. Boojamra, San Francisco, CA (US);

Carina E. Cannizzaro, Foster City, CA (US);

James M. Chen, San Ramon, CA (US);

Xiaowu Chen, Hillsborough, CA (US);

Aesop Cho, Mountain View, CA (US);

Lee S. Chong, Newark, CA (US);

Maria Fardis, San Carlos, CA (US);

Haolun Jin, Foster City, CA (US);

Ralph Hirschmann, Lansdale, PA (US);

Alan X. Huang, San Mateo, CA (US);

Choung U. Kim, San Carlos, CA (US);

Thorsten A. Kirschberg, Redwood City, CA (US);

Christopher P. Lee, San Francisco, CA (US);

William A. Lee, Los Altos, CA (US);

Richard L. Mackman, Millbrae, CA (US);

David Y. Markevitch, San Jose, CA (US);

David A. Oare, Belmont, CA (US);

Vidya K. Prasad, Munich, DE;

Hyung-Jung Pyun, Fremont, CA (US);

Adrian S. Ray, Redwood City, CA (US);

Rosemarie O'Shea, San Carlos, CA (US);

Sundaramoorthi Swaminathan, Burlingame, CA (US);

William J. Watkins, Saratoga, CA (US);

Jennifer R. Zhang, Union City, CA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:

Timothy A. Marquart

Primary Examiner:

Rei-Tsang Shiao

Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07F 9/6561 (2006.01); A61K 31/662 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); A61K 47/48 (2006.01); C07D 205/04 (2006.01); C07D 211/58 (2006.01); C07D 409/06 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 475/00 (2006.01); C07F 9/40 (2006.01); C07F 9/572 (2006.01); C07F 9/58 (2006.01); C07F 9/60 (2006.01); C07F 9/6503 (2006.01); C07F 9/6509 (2006.01); C07F 9/653 (2006.01); C07F 9/6539 (2006.01); C07F 9/655 (2006.01); C07F 9/6553 (2006.01); C07H 15/00 (2006.01); C07H 17/00 (2006.01); C07H 21/00 (2006.01); C07H 19/056 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65616 (2013.01); A61K 31/662 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); A61K 47/48084 (2013.01); C07D 205/04 (2013.01); C07D 211/58 (2013.01); C07D 409/06 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 475/00 (2013.01); C07F 9/4075 (2013.01); C07F 9/5728 (2013.01); C07F 9/582 (2013.01); C07F 9/588 (2013.01); C07F 9/60 (2013.01); C07F 9/653 (2013.01); C07F 9/65037 (2013.01); C07F 9/6539 (2013.01); C07F 9/6561 (2013.01); C07F 9/65515 (2013.01); C07F 9/650941 (2013.01); C07F 9/655354 (2013.01); C07H 15/00 (2013.01); C07H 17/00 (2013.01); C07H 19/056 (2013.01); C07H 19/10 (2013.01); C07H 19/20 (2013.01); C07H 21/00 (2013.01);
Abstract

The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

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