The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2015
Filed:
Jun. 20, 2012
Yonghong Song, Foster City, CA (US);
Qing Xu, Foster City, CA (US);
Shawn M. Bauer, Pacifica, CA (US);
Zhaozhong J. Jia, San Mateo, CA (US);
Mukund Mehrotra, South San Francisco, CA (US);
Anjali Pandey, Fremont, CA (US);
Yonghong Song, Foster City, CA (US);
Qing Xu, Foster City, CA (US);
Shawn M. Bauer, Pacifica, CA (US);
Zhaozhong J. Jia, San Mateo, CA (US);
Mukund Mehrotra, South San Francisco, CA (US);
Anjali Pandey, Fremont, CA (US);
PORTOLA PHARMACEUTICALS, INC., South San Francisco, CA (US);
Abstract
The present invention is directed to compounds of formula I-II and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.