The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2015
Filed:
Dec. 09, 2014
Applicant:
Pfizer Inc., New York, NY (US);
Inventors:
Mary Didiuk, Madison, CT (US);
Kevin J. Filipski, Reading, MA (US);
Angel Guzman-Perez, Belmont, MA (US);
Esther C. Lee, Brookline, MA (US);
Jeffrey A. Pfefferkorn, Acton, MA (US);
Benjamin Stevens, Cambridge, MA (US);
Meihua Tu, Acton, MA (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/58 (2006.01); C07D 241/44 (2006.01); C07D 215/38 (2006.01); C07D 239/94 (2006.01); C07D 217/22 (2006.01); C07D 239/84 (2006.01);
U.S. Cl.
CPC ...
C07D 241/44 (2013.01); C07D 215/38 (2013.01); C07D 217/22 (2013.01); C07D 239/84 (2013.01); C07D 239/94 (2013.01);
Abstract
The present invention provides a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R, R, R, A, A, A, B, B, Band Bare as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.