The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2015

Filed:

May. 18, 2012
Applicants:

Jan Scicinski, Saratoga, CA (US);

Bryan T. Oronsky, Los Altos Hills, CA (US);

Inventors:

Jan Scicinski, Saratoga, CA (US);

Bryan T. Oronsky, Los Altos Hills, CA (US);

Assignee:

EPICENTRX, INC., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/397 (2006.01); C07D 205/04 (2006.01); A61K 31/19 (2006.01); A61K 31/198 (2006.01); A61K 31/215 (2006.01); A61K 31/337 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07D 205/04 (2013.01); A61K 31/19 (2013.01); A61K 31/198 (2013.01); A61K 31/215 (2013.01); A61K 31/337 (2013.01); A61K 31/397 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01);
Abstract

The invention provides organonitro thioether compounds, compositions containing such compounds, isolated organonitro thioether compounds and methods for using such compounds and compositions to treat cancer in a patient. Exemplary organonitro thioether compounds described herein include 2-(3,3-dinitroazetidin-1-yl)-2-oxoethyl thioethers and variants thereof. Another aspect of the invention provides a pharmaceutical composition, comprising a pharmaceutically acceptable carrier and an organonitro thioether compound described herein, such as a compound of Formula I or II. Another aspect of the invention provides a method of treating cancer in a patient. The method comprises administering to a patient in need thereof a therapeutically effective amount of an organonitro thioether compound described herein, such as a compound of Formula I or II, to treat the cancer.


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