The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jun. 07, 1995
Robert G. Pergolizzi, New Milford, NJ (US);
Jannis G. Stavrianopoulos, New York, NY (US);
Elazar Rabbani, New York, NY (US);
Dean L. Engelhardt, New York, NY (US);
Stan Kline, Brooklyn, NY (US);
Paula J. Olsiewski, New York, NY (US);
Robert G. Pergolizzi, New Milford, NJ (US);
Jannis G. Stavrianopoulos, New York, NY (US);
Elazar Rabbani, New York, NY (US);
Dean L. Engelhardt, New York, NY (US);
Stan Kline, Brooklyn, NY (US);
Paula J. Olsiewski, New York, NY (US);
Enzo Diagnostics, Inc., Syosset, NY (US);
Abstract
A method of detecting in a sample an analyte (A) having a molecularly recognizable portion thereon, which comprises: providing (B) a molecular bridging entity having thereon: (i) a portion capable of recognizing the molecularly recognizable portion on the analyte; and (ii) a portion comprising a polynucleotide sequence; and (C) a signalling entity having thereon: (i) a polynucleotide portion capable of annealing to the polynucleotide portion of the bridging entity, thereby to form a stable polynucleotide hybrid, and (ii) a signal generating portion; forming a complex comprising: (1) the analyte (A) complexed through its molecularly recognizable portion to (2) the recognizing portion of the entity (B); the entity (B) being complexed through the polynucleotide portion thereon to (3) the polynucleotide portion of the signalling entity; and detecting a signal by means of the signal generating portion present in the complex.