The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Nov. 17, 2011
Applicants:

Robert M. Archer, Eugene, OR (US);

Frank Hsiung, San Francisco, CA (US);

Paul Patt, Lafayette, CA (US);

Inventors:

Robert M. Archer, Eugene, OR (US);

Frank Hsiung, San Francisco, CA (US);

Paul Patt, Lafayette, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 15/06 (2006.01); G01N 15/14 (2006.01); G01N 15/02 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5094 (2013.01); G01N 15/0606 (2013.01); G01N 15/1463 (2013.01); G01N 2015/0288 (2013.01); G01N 2015/149 (2013.01);
Abstract

Adherent cells bearing characteristics that are detectable only in the adherent state can be sorted on the basis of these characteristics independently of their adherent state, by applying a transformable label to the entire population of cells, both those bearing the characteristics of interest and those not, in their adherent state and identifying the locations of the cells of interest on the adherent surface. The cells of interest, or all cells other than those of interest, are then selectively treated to transform the labels and achieve differentiation between the cells of interest and the remaining cells. All cells are then released from the adherent state and sorted in the same manner as non-adherent cells but on the basis of whether the labels are transformed or not transformed.


Find Patent Forward Citations

Loading…