The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Jun. 17, 2014
Applicant:

Research Foundation of the City University of New York, New York, NY (US);

Inventors:

Ioannis Danias, Staten Island, NY (US);

Hyungsik Lim, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01J 9/00 (2006.01); G01J 4/00 (2006.01); G01N 33/483 (2006.01); G01N 21/63 (2006.01); G01N 21/17 (2006.01); G01N 21/21 (2006.01); A61B 5/00 (2006.01); A61B 3/10 (2006.01); G02B 21/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5044 (2013.01); A61B 3/10 (2013.01); A61B 5/4848 (2013.01); G01J 4/00 (2013.01); G01J 9/00 (2013.01); G01N 21/1717 (2013.01); G01N 21/21 (2013.01); G01N 21/63 (2013.01); G01N 21/636 (2013.01); G01N 33/4833 (2013.01); G01N 33/5008 (2013.01); G01J 2009/002 (2013.01); G01J 2009/004 (2013.01); G01N 2021/1734 (2013.01); G02B 21/002 (2013.01);
Abstract

The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.


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