The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Dec. 16, 2011
Applicants:

Atanu Sengupta, New Haven, CT (US);

Frank E. Inscore, Bristol, CT (US);

Chetan Shende, Ellington, CT (US);

Michael J. Donahue, Middletown, CT (US);

Stuart Farquharson, Meriden, CT (US);

Inventors:

Atanu Sengupta, New Haven, CT (US);

Frank E. Inscore, Bristol, CT (US);

Chetan Shende, Ellington, CT (US);

Michael J. Donahue, Middletown, CT (US);

Stuart Farquharson, Meriden, CT (US);

Assignee:

REAL-TIME ANALYZERS, INC., Middletown, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/65 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 21/658 (2013.01); G01N 33/58 (2013.01); G01N 33/587 (2013.01);
Abstract

A SERS method and apparatus employ a sample device having support structure including a first material containing a SER-active metal functionalized with a binding agent having specific capability for binding a designated target analyte. An analyte sample is introduced upon the functionalized SER-active metal; conditions to effect binding of the target analyte to the binding agent are maintained; unbound chemicals, biochemicals, or biologicals are removed; a second SER-active material is introduced to cause it to attach to the bound target analyte; the support structure is irradiated to generate a SER spectrum, with the first and second SER-active materials acting in concert; and the SER spectrum is detected and analyzed to determine the presence and quantity of the target analyte. Alternatively, the second SER-active material may be functionalized with a binding agent, with the procedure being modified accordingly.


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