The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Oct. 14, 2010
Applicants:

Yeo Joon Yoon, Seoul, KR;

Sung Ryeol Park, Goyang-si, KR;

Je Won Park, Goyang-si, KR;

Jae Kyung Sohng, Asan-si, KR;

Inventors:

Yeo Joon Yoon, Seoul, KR;

Sung Ryeol Park, Goyang-si, KR;

Je Won Park, Goyang-si, KR;

Jae Kyung Sohng, Asan-si, KR;

Assignee:

iNtRON Biotechnology, Inc., Seongnam-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/22 (2006.01); C12P 19/48 (2006.01); A61K 31/351 (2006.01); A61K 31/7036 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12P 19/485 (2013.01); A61K 31/351 (2013.01); A61K 31/7036 (2013.01); C07H 15/22 (2013.01); C12N 15/52 (2013.01);
Abstract

Vectors expressing kanA-kanB-kanK and other kanamycin production-related genes,<i/> species recombinant bacteria transformed with the vectors, a method of producing kanamycin antibiotics by the bacteria, and a new kanamycin compound produced by the bacterium are provided. With the use of the recombinant bacteria of the present invention, the direct fermentative biosynthesis of amikacin and tobramycin as semi-synthetic kanamycins is possible, and the yield of kanamycin B as a precursor of the semi-synthetic kanamycin is improved.


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