The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Aug. 08, 2014
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Inchan Kwon, Pasadena, CA (US);
David Tirrell, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 15/113 (2010.01); C12N 9/00 (2006.01); C12P 21/02 (2006.01); C07H 21/02 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07H 21/02 (2013.01); C12N 9/93 (2013.01); C12N 15/70 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C12N 2310/10 (2013.01);
Abstract
The invention provides a method of incorporating nonstandard amino acids into a protein by utilizing a modified aminoacyl-tRNA synthetase to charge the nonstandard amino acid to a modified tRNA, which forms strict Watson-Crick base-pairing with a codon that normally forms wobble base-pairing with natural tRNAs.