The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jun. 23, 2011
Takuya Ueda, Tokyo, JP;
Takashi Kanamori, Chiba, JP;
Kanehisa Kojoh, Chiba, JP;
Shizue Katoh, Chiba, JP;
Akira Miyakoshi, Chiba, JP;
Takuya Ueda, Tokyo, JP;
Takashi Kanamori, Chiba, JP;
Kanehisa Kojoh, Chiba, JP;
Shizue Katoh, Chiba, JP;
Akira Miyakoshi, Chiba, JP;
The University of Tokyo, Tokyo, JP;
GeneFrontier Corporation, Kashiwa, JP;
Abstract
The present invention provides a method of producing a maturated oligonucleotide library, including a step of obtaining a terminal-modified product of a maturation target oligonucleotide library, including adding a tag sequence to the 5' terminus of the maturation target oligonucleotide library and an arrest sequence, which stalls translation elongation on a ribosome, to the 3′ terminus of the maturation target oligonucleotide library, a step of transcribing the terminal-modified sequence product to give a transcript, and a step of in vitro translation for translating the transcript in vitro, wherein the maturation target oligonucleotide library is a random oligonucleotide library.