The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Jan. 11, 2008
Applicants:

Masayo Takahashi, Kobe, JP;

Fumitaka Osakada, Kobe, JP;

Michiko Mandai, Kobe, JP;

Hanako Ikeda, Kyoto, JP;

Inventors:

Masayo Takahashi, Kobe, JP;

Fumitaka Osakada, Kobe, JP;

Michiko Mandai, Kobe, JP;

Hanako Ikeda, Kyoto, JP;

Assignee:

RIKEN, Wako, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 5/0793 (2010.01); C12N 5/079 (2010.01); C12N 5/0797 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/062 (2013.01); C12N 5/0621 (2013.01); C12N 5/0623 (2013.01); A61K 35/12 (2013.01); C12N 2500/33 (2013.01); C12N 2500/99 (2013.01); C12N 2501/113 (2013.01); C12N 2501/115 (2013.01); C12N 2501/16 (2013.01); C12N 2501/385 (2013.01); C12N 2501/415 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/08 (2013.01); C12N 2533/00 (2013.01);
Abstract

The present invention provides a method of producing primate retinal progenitor cells, comprising culturing primate embryonic stem cells as suspended aggregates in a serum-free medium, and obtaining retinal progenitor cells from the culture. The present invention further provides a method of producing photoreceptor precursor cells, comprising culturing isolated retinal progenitor cells differentiated from embryonic stem cells, under adhesive conditions, in the presence of a gamma secretase inhibitor, and obtaining a photoreceptor precursor from the culture.


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