The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Sep. 16, 2011
Applicants:

Felix Cleemann, Heidelberg, DE;

Ulrich Hersel, Heidelberg, DE;

Torben Lessman, Mannheim, DE;

Harald Rau, Heidelberg, DE;

Inventors:

Felix Cleemann, Heidelberg, DE;

Ulrich Hersel, Heidelberg, DE;

Torben Lessman, Mannheim, DE;

Harald Rau, Heidelberg, DE;

Assignee:

SANOFI-AVENTIS DEUTSCHLAND GMBH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/00 (2006.01); A61P 3/10 (2006.01); C07K 17/08 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 17/08 (2013.01); A61K 47/48215 (2013.01); A61K 47/48338 (2013.01); A61K 47/48784 (2013.01);
Abstract

The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an exendin linker conjugate D-L, wherein D represents an exendin moiety; and -Lis represented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the exendin moiety by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by exendin.


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