The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Jun. 22, 2007
Applicants:

Thomas Blankenstein, Berlin, DE;

Wolfgang Uckert, Berlin, DE;

Elisa Kieback, Berlin, DE;

Jehad Charo, Berlin, DE;

Inventors:

Thomas Blankenstein, Berlin, DE;

Wolfgang Uckert, Berlin, DE;

Elisa Kieback, Berlin, DE;

Jehad Charo, Berlin, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 19/00 (2006.01); C07H 21/04 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01); C12P 21/02 (2006.01); A61K 38/17 (2006.01); C12N 15/62 (2006.01); C12N 15/79 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61K 35/12 (2015.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 38/177 (2013.01); C12N 15/62 (2013.01); C12N 15/79 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); A61K 2035/124 (2013.01); A61K 2039/5158 (2013.01); C07K 2319/20 (2013.01); C07K 2319/21 (2013.01); C07K 2319/23 (2013.01); C07K 2319/40 (2013.01); C07K 2319/41 (2013.01); C07K 2319/43 (2013.01);
Abstract

The present invention relates to a method for selecting a host cell population expressing a functional fusion protein comprising at least one epitope-providing amino acid sequence (epitope-tag) and the amino acid sequence of a protein that is expressed on the surface of said host cell. Preferably, the amino acid sequence comprises an alpha or beta chain of a T-cell receptor. The present invention further relates to uses of said functional T-cell receptor (TCR) alpha or beta chain fusion protein in medicine, in particular in adoptive transfer.


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