The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Apr. 13, 2012
Applicants:
Dominique Burnouf, Brumath, FR;
Annick Stote, Strasbourg, FR;
Gilles Guichard, Gradignan, FR;
Jérôme Wagner, Strasbourg, FR;
Vincent Olieric, Endingen, CH;
Inventors:
Dominique Burnouf, Brumath, FR;
Annick Stote, Strasbourg, FR;
Gilles Guichard, Gradignan, FR;
Jérôme Wagner, Strasbourg, FR;
Vincent Olieric, Endingen, CH;
Assignee:
Centre National de la Recherche Scientifique, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); C07K 7/06 (2006.01); C07K 14/245 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 38/08 (2013.01); C07K 14/195 (2013.01); C07K 14/245 (2013.01);
Abstract
The present invention relates to compounds which bind to the hydrophobic pocket of the β clamp, i.e., to the surface of the β ring with which said protein interacts with other proteins of the bacterial replication complex during DNA replication. These compounds are derived from the acetylated peptide AcQLDLF (P6) to improve their affinity to their target.