The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Feb. 13, 2012
Applicants:

Stéphanie Blanchard, Singapore, SG;

Kantharaj Ethirajulu, Singapore, SG;

Cheng Hsia Angeline Lee, Sinagpore, SG;

Harish Kumar Mysore Nagaraj, Singapore, SG;

Anders Poulsen, Sinagpore, SG;

Eric T. Sun, Singapore, SG;

Yee Ling Evelyn Tan, Singapore, SG;

EE Ling Teo, Singapore, SG;

Anthony Deodaunia William, Singapore, SG;

Inventors:

Stéphanie Blanchard, Singapore, SG;

Kantharaj Ethirajulu, Singapore, SG;

Cheng Hsia Angeline Lee, Sinagpore, SG;

Harish Kumar Mysore Nagaraj, Singapore, SG;

Anders Poulsen, Sinagpore, SG;

Eric T. Sun, Singapore, SG;

Yee Ling Evelyn Tan, Singapore, SG;

Ee Ling Teo, Singapore, SG;

Anthony Deodaunia William, Singapore, SG;

Assignee:

S*BIO Pte Ltd, Singapore Science Park II, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/06 (2006.01); C07D 498/08 (2006.01); C07D 498/16 (2006.01); C07D 498/18 (2006.01); C07D 515/16 (2006.01); C07D 515/18 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); A61K 31/519 (2013.01); C07D 498/06 (2013.01); C07D 498/16 (2013.01); C07D 498/18 (2013.01); C07D 515/16 (2013.01); C07D 515/18 (2013.01);
Abstract

The present invention relates to pyrimidine compounds that are useful as anti-proliferative agents. More particularly, the present invention relates to heteroalkyl linked and substituted pyrimidine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative disorders including tumors and cancers as well as other conditions or disorders associated with kinases.


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