The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Aug. 20, 2012
Applicants:

Rongzhen Xu, Zhejiang, CN;

Frank Rong, Zhajiang, CN;

Fuwen Xie, Fujian, CN;

Hongxi Lai, Fujian, CN;

Inventors:

Rongzhen Xu, Zhejiang, CN;

Frank Rong, Zhajiang, CN;

Fuwen Xie, Fujian, CN;

Hongxi Lai, Fujian, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/18 (2006.01); C07D 491/22 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); C07D 491/147 (2013.01); C07D 491/18 (2013.01);
Abstract

The present invention belongs to the field of natural medicine and pharmaceutical chemistry and specifically relates to novel 5-substituted tetrandrine derivatives of formula (I) and a pharmaceutically acceptable adduct, complex and salt thereof, to a process for the preparation of these compounds, pharmaceutical compositions containing such compounds and their use in preparing antineoplastic medicaments.


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