The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
May. 12, 2008
Gerardo Castillo, Bothell, WA (US);
Beth Nguyen, Gurnee, IL (US);
Paula Choi, Seattle, WA (US);
Lesley Larsen, Dunedin, NZ;
Stephen Lorimer, Dunedin, NZ;
Alan Snow, Lynnwood, WA (US);
Gerardo Castillo, Bothell, WA (US);
Beth Nguyen, Gurnee, IL (US);
Paula Choi, Seattle, WA (US);
Lesley Larsen, Dunedin, NZ;
Stephen Lorimer, Dunedin, NZ;
Alan Snow, Lynnwood, WA (US);
PROTEOTECH INC., Kirkland, WA (US);
Abstract
Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus. The isolated and/or synthesized procyanidin B2 is used to treat amyloid disease, such as Alzheimer's disease and Parkinson's disease as well as improve cognitive performance and increase learning and memory in Alzheimer's patients. Pharmaceutical compositions containing the synthesized and/or isolated procyanidin B2 are also disclosed.