The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Oct. 26, 2012
Applicants:

Michael John Boyd, Winchester, MA (US);

Jean-francois Chiasson, St-Constant, CA;

Sheldon Crane, Pierrefonds, CA;

André Giroux, Ste-Anne-de-Bellevue, CA;

Inventors:

Michael John Boyd, Winchester, MA (US);

Jean-Francois Chiasson, St-Constant, CA;

Sheldon Crane, Pierrefonds, CA;

André Giroux, Ste-Anne-de-Bellevue, CA;

Assignee:

Merck Canada Inc., Kirkland, Province of Quebec, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/381 (2006.01); C07D 333/10 (2006.01); C07D 333/20 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 277/28 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 333/20 (2013.01); C07B 59/002 (2013.01); C07D 277/28 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Compounds of Formula I are disclosed: wherein A, R, R, R, R, R, R, Rand Rare defined herein. The compounds encompassed by Formula I include compounds which are HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.


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