The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Aug. 20, 2009
Applicants:

Shinji Marumoto, Tokyo, JP;

Toyoki Nishimata, Tokyo, JP;

Masayuki Ebisawa, Tokyo, JP;

Yusuke Asoh, Tokyo, JP;

Yasuo Fukushima, Tokyo, JP;

Mikio Kato, Tokyo, JP;

Inventors:

Shinji Marumoto, Tokyo, JP;

Toyoki Nishimata, Tokyo, JP;

Masayuki Ebisawa, Tokyo, JP;

Yusuke Asoh, Tokyo, JP;

Yasuo Fukushima, Tokyo, JP;

Mikio Kato, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); C07D 257/04 (2006.01); C07C 217/54 (2006.01); C07C 217/74 (2006.01); C07C 229/16 (2006.01); C07C 229/18 (2006.01); C07C 229/46 (2006.01); C07C 237/36 (2006.01); C07C 323/52 (2006.01);
U.S. Cl.
CPC ...
C07D 257/04 (2013.01); C07C 217/54 (2013.01); C07C 217/74 (2013.01); C07C 229/16 (2013.01); C07C 229/18 (2013.01); C07C 229/46 (2013.01); C07C 237/36 (2013.01); C07C 323/52 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01);
Abstract

Provided is a therapeutic agent for hyperparathyroidism, renal osteodystrophy, hypercalcemia and the like, which has a CaSR activating (agonist) action. A compound represented by the following general formula (1): [wherein, Ar which is a partial structure in the general formula (1) represents a phenyl group or a naphthyl group; Rand Rare the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; Rand Rare the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; A represents a single bond, an oxygen atom, or the like; B represents a single bond, a C1-C4 alkanediyl group, or the like; Z represents a carboxyl group or a tetrazolyl group; and m represents an integer of 1 to 3] or a pharmacologically acceptable salt thereof.


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