The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Sep. 20, 2013
Bristol-myers Squibb Company, Princeton, NJ (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Weifang Shan, Princeton, NJ (US);
James Aaron Balog, Lambertsville, NJ (US);
Claude A. Quesnelle, Skillman, NJ (US);
Wen-Ching Han, Newtown, PA (US);
George V. DeLucca, Pennington, NJ (US);
Daniel O'Malley, New Hope, PA (US);
Brian E. Fink, Yardley, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I): wherein: Ris phenyl, fluorophenyl, chlorophenyl, trifluorophenyl, methylisoxazolyl, or pyridinyl; Ris H, CH, CH(cyclopropyl), pyridinyl, chloropyridinyl, or methoxypyridinyl: and R, R, y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer.