The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Apr. 22, 2011
Applicants:

Luke W. Ashcraft, San Francisco, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Scott Collibee, San Carlos, CA (US);

Chihyuan Chuang, Millbrae, CA (US);

Jeff Gardina, South San Francisco, CA (US);

Bradley P. Morgan, Moraga, CA (US);

Alex R. Muci, San Francisco, CA (US);

Xiangping Qian, Foster City, CA (US);

Antonio Romero, San Mateo, CA (US);

Jeffrey Warrington, San Mateo, CA (US);

Zhe Yang, Daly City, CA (US);

Inventors:

Luke W. Ashcraft, San Francisco, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Scott Collibee, San Carlos, CA (US);

Chihyuan Chuang, Millbrae, CA (US);

Jeff Gardina, South San Francisco, CA (US);

Bradley P. Morgan, Moraga, CA (US);

Alex R. Muci, San Francisco, CA (US);

Xiangping Qian, Foster City, CA (US);

Antonio Romero, San Mateo, CA (US);

Jeffrey Warrington, San Mateo, CA (US);

Zhe Yang, Daly City, CA (US);

Assignee:

Cytokinetics, Inc., South San Francisco, CA (US);

Attorney:
Int. Cl.
CPC ...
C07D 253/07 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); A61K 31/53 (2006.01); A61K 31/427 (2006.01); A61K 31/4427 (2006.01); A61P 21/00 (2006.01); A61P 21/04 (2006.01); C07D 213/75 (2006.01); C07D 213/78 (2006.01); C07D 213/82 (2006.01); C07D 215/48 (2006.01); C07D 403/04 (2006.01); C07D 417/04 (2006.01); C07D 213/74 (2006.01); C07D 215/38 (2006.01); C07D 403/10 (2006.01);
U.S. Cl.
CPC ...
C07D 213/74 (2013.01); C07D 213/75 (2013.01); C07D 213/78 (2013.01); C07D 213/82 (2013.01); C07D 215/38 (2013.01); C07D 215/48 (2013.01); C07D 253/07 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01);
Abstract

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, X, Z, Z, Z, Zand m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.


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