The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Aug. 17, 2012
Applicants:
Christoph Stein, Berlin, DE;
Marcus Weber, Berlin, DE;
Christian Zöllner, Hamburg, DE;
Olga Scharkoi, Berlin, DE;
Inventors:
Christoph Stein, Berlin, DE;
Marcus Weber, Berlin, DE;
Christian Zöllner, Hamburg, DE;
Olga Scharkoi, Berlin, DE;
Assignees:
CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN, Berlin, DE;
KONRAD-ZUSE-INSTITUT, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 211/58 (2006.01);
U.S. Cl.
CPC ...
C07D 211/58 (2013.01);
Abstract
The invention relates to fluorinated fentanyl derivatives that function as opioid receptor agonists, which activate target opioid receptors in a pH-dependent manner, and are thus selective for the receptors in inflamed (acidic) milieu; uses thereof and pharmaceutical compositions comprising them.