The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jan. 06, 2011
Sung Wuk Kim, Gyeonggi-do, KR;
Sung Soo Jun, Gyeonggi-do, KR;
Chang Hee Min, Seoul, KR;
SE Hwan Park, Daejeon, KR;
Yong Eun Kim, Daejeon, KR;
Duck Kim, Daegu, KR;
Ji Sun Lee, Daejeon, KR;
Ju Hoon OH, Gangwon-so, KR;
Sung Wuk Kim, Gyeonggi-do, KR;
Sung Soo Jun, Gyeonggi-do, KR;
Chang Hee Min, Seoul, KR;
Se Hwan Park, Daejeon, KR;
Yong Eun Kim, Daejeon, KR;
Duck Kim, Daegu, KR;
Ji Sun Lee, Daejeon, KR;
Ju Hoon Oh, Gangwon-so, KR;
Hanall Biopharma Co., Ltd., , KR;
Abstract
A biguanide derivative compound with N4-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK and inhibition of cancer cell proliferation in a low dose, compared with conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.