The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Apr. 24, 2014
Applicants:

Children's Hospital & Research Center AT Oakland, Oakland, CA (US);

Research Foundation of the City University of New York, New York, NY (US);

Inventors:

Julie D. Saba, Oakland, CA (US);

Henrik Fyrst, Oakland, CA (US);

Robert Bittman, Roslyn Heights, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 215/24 (2006.01); A61K 31/133 (2006.01); A61K 8/68 (2006.01); A61K 31/352 (2006.01); A61K 31/436 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07C 215/24 (2013.01); A61K 8/68 (2013.01); A61K 31/133 (2013.01); A61K 31/352 (2013.01); A61K 31/436 (2013.01); A61K 31/5377 (2013.01);
Abstract

The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes and infection with intracellular bacteria. The invention is also directed to methods of using the compounds and pharmaceutical compositions comprising the compounds in treating these diseases.


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