The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jun. 19, 2012
Jing Zeng, Rockville, MD (US);
Charles George Drake, Baltimore, MD (US);
Drew M. Pardoll, Brookeville, MD (US);
Michael Lim, Reisterstown, MD (US);
Jing Zeng, Rockville, MD (US);
Charles George Drake, Baltimore, MD (US);
Drew M. Pardoll, Brookeville, MD (US);
Michael Lim, Reisterstown, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.